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臨床用藥|血培養(yǎng) MSSA,選擇萬古、利奈還是頭孢唑啉?( 二 )

  • MSSA 菌血癥首選耐酶青霉素與一代頭孢類 , 萬古霉素、利奈唑胺不作為首選;
  • 金葡菌血癥非常復雜 , 復發(fā)率死亡率較高 , 需要多學科協(xié)作 , 感染灶控制與引流非常重要;
  • 抗菌療程:無并發(fā)癥的血培養(yǎng)轉(zhuǎn)陰后 14 天 , 有并發(fā)癥的療程至少 4-6 周 。
投稿 | drugs@dxy.cn 題圖 | 站酷海洛參考文獻
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8. Small PM, Chambers HF. Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users. Antimicrob Agents Chemother 1990; 34:122731.
9. Stryjewski ME, Szczech LA, Benjamin DK Jr., et al Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis dependent patients with methicillin-susceptible Staphylococcus aureusbacteremia. Clin Infect Dis 2007; 44:1906.
10. Chang FY, Peacock JE Jr., Musher DM, et al Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospectivemulticenter study. Medicine(Baltimore)2003;82:3339.
11. Kim SH, Kim KH, Kim HB, et al Outcome of vancomycin treatment in patients with methicillin-susceptible Staphylococcus aureus bacteremia.Antimicrob Agents Chemother 2008; 52:1927.
12. Lodise TP Jr., McKinnon PS, Levine DP, et al Impact of empirical therapy selection on outcomes of intravenous drug users with in fective endocarditis caused by methicillin-susceptible Staphylococcusaureus. Antimicrob Agents Chemother 2007; 51:37313.

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